Kvasny Prum. 1977; 23(4): 84-86 | DOI: 10.18832/kp1977013

The use of continuous cultivation during biosynthesis of amino acids. II. L-lysine.Peer-reviewed article

P. PILÁT

In the research of microbial synthesis of amino acids, the most attention has been devoted to L-lysine. In course of recent years the continuous process has been intensively studied particularly inUSSR. The auxotroph mutant used, rich cultivation broths, pH-value round 7 as well as the proper princip of continuous cultivation are factors that make a long-terms maintenance of  properties of the production microorganisms and the maintenance of the continuous cultivation sterility considerably difficult. The complexity of the 3-4 stage systems proposed, intensifies these problems father on.
(In Czech, English summary only)

Keywords: aminoacids, continuous cultivation, L-lysine

Published: April 1, 1977