Kvasny Prum. 1989; 35(6): 169-170 | DOI: 10.18832/kp1989023

Fermentation of clavulanic acid.Peer-reviewed article

M. ÚLEHLOVÁ, H. RYŠÁNOVÁ

Strains Streptomyces jumonjinensis NRRL 5741 and Streptomyces species ATCC 31450 were used for the laboratory flask preparation of the b-lactamase inhibitor clavulanic acid. Concentration of the clavulanic acid in fermentation broths was estimated by a microbiological diffusion method in the maximum level 20 mg/ml.
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Keywords: clavulanic acid, fermentation, microbiological diffusion method

Published: June 1, 1989