Kvasny Prum. 1982; 28(12): 278-281 | DOI: 10.18832/kp1982057

Two-stage continuous biosynthesis of L-lysine.Peer-reviewed article

P. PILÁT, F. PALEČKOVÁ

The conditions of the L-lysine continuous biosynthesis was studied using the suppressor mutant Brevibacterium sp. CCM AO 6/79. In contrast with literature data (multi-stag continuous systems the production process was simplified maintaining the optimal conditions of amino acid biosynthesis. The highest yields were achieved using the two-stage continuous culture with the semicontinuous regime in the second stage. When compared with batch culture the production of L-lysine was increased roughly by 70 %.
(In Czech, English summary only)

Keywords: L-lysine, continuous biosynthesis, Brevibacterium sp

Published: December 1, 1982