Kvasny Prum. 1985; 31(7-8): 169-170 | DOI: 10.18832/kp1985037

Controlled evolution of utilization of unnatural substrates by bacteria.Peer-reviewed article

P. KYSLÍK

The mutants with new phenotype are selected and accumulated in batch and continuous cultures if the growth of prokaryotes is limited by a source of carbon and energy rarely-existing in nature, by an unnatural substrate. Such a phenotype is a result of the presence of new enzyme activity and changes in the regulation of the expression of operons of catabolic endoenzymes. The culture response to the selection pressure has no occasional character and is subjected to define laws.
(In Czech, English summary only)

Keywords: mutants, phenotype, microorganisms

Published: July 1, 1985